Benzaldehyde → HCID 178510596, compound

Participants

Reaction Steps

To a stirred solution of 4-amino-1H-imidazol-5-carbonitrile (1.1 g, 0.01 mole) in 25 ml of methanol was added 1.1 grams of benzaldehyde. The reaction mixture was then stirred at ambient temperature for 16 hours, heated on a steam bath for 20 minutes, cooled to ambient temperature, then stirred with 25 ml of diethyl ether. The mixture was filtered and the filtrate concentrated under reduced pressure to a residual solid. The solid was recrystallized from toluene-butanol to give 5-cyano-4-phenylmethylimino-1H-imidazole (0.92 g; mp, 200°-202°).

Provenance & Evidence