Sodium Carbonate → HCID 20565165, compound

Participants

Reaction Steps

0.037 mol (10 g) of 4-acetylamino-N-(β-mesylaminoethyl)-aniline is dissolved in 31 ml of boiling water. 7.4 g of sodium carbonate and 0.148 mol (18.5 g) of glycol bromohydrin are added, whilst stirring. After stirring for 4 hours in a boiling water bath, the reaction medium is filtered and the filtrate is then left to stand for 48 hours at 0° C. The 4-acetylamino-N-(β-hydroxyethyl)-N-mesylaminoethylaniline which has precipitated in crystalline form is filtered off. After recrystallisation from boiling water and drying in vacuo, the product melts at 118° C.

Provenance & Evidence