1-Hexanamine, hydrochloride → HCID 178444829, compound

HRID 1285325Notes

Reaction equation

HRID 1285325 reaction equation
Cl.[CH2:2]([NH2:8])[CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].[N-:9]([C:12]#[N:13])[C:10]#[N:11].[Na+]>C(O)CCC>[C:10]([NH:9][C:12](=[NH:13])[NH:8][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7])#[N:11]

Participants

4

Reactant 2

HCID 673421-Hexanamine, hydrochlorideHCID 4350929Sodium dicyanamide

Product 1

HCID 178444829HCID 178444829, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

A mixture of hexylamine hydrochloride (63.5 g.), sodium dicyanamide (44.5 g.) and butanol (200 ml.) was heated under reflux for 18 hours and then cooled. The mixture was filtered and the filtrate was evaporated to dryness. The residue was stirred with water and the insoluble solid was collected and crystallised from aqueous ethanol to give 3-cyano-1-hexylguanidine m.p. 103°-105°.

Workup

  1. temperaturewas heated
  2. temperatureunder reflux for 18 hours
  3. temperaturecooled
  4. filtrationThe mixture was filtered
  5. customthe filtrate was evaporated to dryness
  6. customthe insoluble solid was collected
  7. customcrystallised from aqueous ethanol

Sources & evidence

ORD record
ord-202fd648951f4a14b7b094f0c4e1a414
Source dataset
uspto-grants-1986_01
Patent number
US04567174

Reaction notes

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