Phosphorus pentachloride → Ethoxy(4-phenylbutyl)phosphinyl chloride

HRID 1285468Notes

Reaction equation

HRID 1285468 reaction equation
[CH2:1]([O:3][P:4]([CH2:9][CH2:10][CH2:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)(=O)[O:5]CC)[CH3:2].P(Cl)(Cl)(Cl)(Cl)[Cl:20]>C1C=CC=CC=1>[CH2:1]([O:3][P:4]([Cl:20])([CH2:9][CH2:10][CH2:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 24819Phosphorus pentachlorideHCID 13102400Diethyl 4-phenylbutylphosphonate

Product 1

HCID 15591238Ethoxy(4-phenylbutyl)phosphinyl chloride

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A mixture of diethyl(4-phenylbutyl)phosphonate (0.73 g., 2.6 mmole), benzene (10 ml.) and phosphorus pentachloride (1.0 eq.) is refluxed under argon for 30 minutes. The benzene and phosphorus oxychloride are removed in vacuo to give ethoxy(4-phenylbutyl)phosphinyl chloride.

Workup

  1. temperatureis refluxed under argon for 30 minutes
  2. customThe benzene and phosphorus oxychloride are removed in vacuo

Sources & evidence

ORD record
ord-1be57c060dbe4ae68593003a04f3e4c1
Source dataset
uspto-grants-1986_01
Patent number
US04567167

Reaction notes

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