HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-3-amino-2-oxohexahydro-1H-azepine-1-acetic acid, phenylmethyl ester → (S)-hexahydro-3-[[ethoxy(4-phenylbutyl)phosphinyl]amino]-2-oxo-1H-azepine-1-acetic acid, phenylmethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-3-amino-2-oxohexahydro-1H-azepine-1-acetic acid, phenylmethyl ester | HCID 10660087 | — |
| Reactant | Ethoxy(4-phenylbutyl)phosphinyl chloride | HCID 15591238 | — |
| Product | (S)-hexahydro-3-[[ethoxy(4-phenylbutyl)phosphinyl]amino]-2-oxo-1H-azepine-1-acetic acid, phenylmethyl ester | HCID 86740221 | — |
Reaction Steps
Ethoxy(4-phenylbutyl)phosphinyl chloride is reacted with (S)-3-amino-2-oxo-hexahydro-1H-azepine-1-acetic acid, phenylmethyl ester according to the procedure of Example 2(e) to give (S)-hexahydro-3-[[ethoxy(4-phenylbutyl)phosphinyl]amino]-2-oxo-1H-azepine-1-acetic acid, phenylmethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04567167 |
| Source dataset | uspto-grants-1986_01 |
| ORD ID | ord-5221a49037a049e0bbd019094d2f5356 |
| Source note | uspto-grants-1986_01 |