Cesium carbonate → HCID 21280526, compound

Participants

Reaction Steps

A suspension of 3.3 g of picolyl chloride hydrochloride (Aldrich 16,270-1), 1-(3-hydroxyphenyl)-1-hexanol (3.9 g.), cesium carbonate (16.3 g.), cesium iodide (trace) and acetone was refluxed for 40 hours. The reaction was filtered through a pad of celite and silica gel and the solvent removed in vacuo. The remaining oil was dissolved in ethyl ether, filtered through celite and silica gel and treated with ethereal hydrochloric acid. The resulting white precipitate was filtered, washed (ethyl ether) and dried giving 4.2 g (66% yield) of solid, m.p. 164°-165° C.

Provenance & Evidence