HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylamine → HCID 178483903, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | HCID 178506251 | HCID 178506251 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 178483903 | HCID 178483903 | — |
Reaction Steps
A solution of 2-[4-(2,3-epoxypropoxy)phenyl]-4-trifluoromethylimidazole in triethylamine (15 ml) is added 1.1 equivalents of a dimethylamine. This solution is refluxed until reaction is complete as indicated by TLC. The solvent is removed under reduced pressure and the residue recrystallized to yield 2-[4-(3-dimethylamino-2-hydroxypropoxy)phenyl]-4-trifluoromethylimidazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04567276 |
| Source dataset | uspto-grants-1986_01 |
| ORD ID | ord-25e325be99034234b5df0aa6fca1fe25 |
| Source note | uspto-grants-1986_01 |