HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Bromopyridine → Biphenyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Bromopyridine | HCID 12286 | — |
| Reactant | 1-Methyl-3-phenylpropylamine | HCID 31160 | — |
| Reagent | tert-Butylimino-tri(pyrrolidino)phosphorane | HCID 3856267 | — |
| Reagent | HCID 178505365 | HCID 178505365 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | Biphenyl | HCID 7095 | — |
| Product | 3-Bromopyridine | HCID 12286 | — |
| Product | 1-Methyl-3-phenylpropylamine | HCID 31160 | — |
| Product | N-(4-phenylbutan-2-yl)pyridin-3-amine | HCID 43190526 | — |
Reaction Steps
The Mosquito was used to combine the source plate solutions by multi-aspiration of 250 nL of each of the four reaction components and then to dose the resulting reaction mixture (1 uL) into a 1536-well plate
Provenance & Evidence
| DOI | 10.1126/science.1259203 |
|---|---|
| Source dataset | HTE Pd-catalyzed cross-coupling screen |
| ORD ID | ord-b08142f574b3456487ef717068c3de4e |
| Source note | HTE Pd-catalyzed cross-coupling screen |