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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1285732Generated: October 27, 2026

Aniline → Aniline

https://huagongshe.com/reaction/1285732

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnilineHCID 6115—
Reactant3-BromopyridineHCID 12286—
Reagent1,8-Diazabicyclo(5.4.0)undec-7-eneHCID 81184—
ReagentHCID 178505363HCID 178505363—
SolventDimethyl SulfoxideHCID 679—
ProductAnilineHCID 6115—
ProductBiphenylHCID 7095—
Product3-BromopyridineHCID 12286—
ProductPhenyl-pyridin-3-yl-amineHCID 4712169—

Reaction Steps

The Mosquito was used to combine the source plate solutions by multi-aspiration of 250 nL of each of the four reaction components and then to dose the resulting reaction mixture (1 uL) into a 1536-well plate

Provenance & Evidence

DOI10.1126/science.1259203
Source datasetHTE Pd-catalyzed cross-coupling screen
ORD IDord-d4283fa79f2949a886b8138999a01edc
Source noteHTE Pd-catalyzed cross-coupling screen