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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1285771Generated: October 31, 2026

Aniline → Aniline

https://huagongshe.com/reaction/1285771

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnilineHCID 6115—
Reactant3-BromopyridineHCID 12286—
Reagent2-((1,1-Dimethylethyl)imino)-N,N-diethylhexahydro-1,3-dimethyl-2lambda5-1,3,2-diazaphosphorin-2-amineHCID 3513851—
ReagentHCID 178439017HCID 178439017—
SolventDimethyl SulfoxideHCID 679—
ProductAnilineHCID 6115—
ProductBiphenylHCID 7095—
Product3-BromopyridineHCID 12286—
ProductPhenyl-pyridin-3-yl-amineHCID 4712169—

Reaction Steps

The Mosquito was used to combine the source plate solutions by multi-aspiration of 250 nL of each of the four reaction components and then to dose the resulting reaction mixture (1 uL) into a 1536-well plate

Provenance & Evidence

DOI10.1126/science.1259203
Source datasetHTE Pd-catalyzed cross-coupling screen
ORD IDord-c95df8a18e2b40199ac03088605820ad
Source noteHTE Pd-catalyzed cross-coupling screen