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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1286123Generated: October 27, 2026

3-Bromopyridine → Biphenyl

https://huagongshe.com/reaction/1286123

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromopyridineHCID 12286—
ReactantBenzeneethanimidamideHCID 27787—
Reagent7-Methyl-1,5,7-triazabicyclo[4.4.0]dec-5-eneHCID 123583—
ReagentHCID 178505365HCID 178505365—
SolventDimethyl SulfoxideHCID 679—
ProductBiphenylHCID 7095—
Product3-BromopyridineHCID 12286—
ProductBenzeneethanimidamideHCID 27787—
ProductHCID 178510790HCID 178510790—

Reaction Steps

The Mosquito was used to combine the source plate solutions by multi-aspiration of 250 nL of each of the four reaction components and then to dose the resulting reaction mixture (1 uL) into a 1536-well plate

Provenance & Evidence

DOI10.1126/science.1259203
Source datasetHTE Pd-catalyzed cross-coupling screen
ORD IDord-231f4cde64884ef9a1194763c8bf79b2
Source noteHTE Pd-catalyzed cross-coupling screen