3-(4-Nitrophenoxy)propane-1,2-diol → 3-(4-Aminophenoxy)-1,2-propanediol

Participants

Reaction Steps

A solution of 3-(4-nitrophenoxy)propane-1,2-diol (5.0 g) in absolute ethanol (250 ml) was hydrogenated at atmospheric pressure in the presence of 10% palladium on charcoal (150 mg). After the uptake of hydrogen had ceased, the catalyst was removed by filtration. The filtrate was evaporated under reduced pressure to give 3-(4-aminophenoxy)propane-1,2-diol as a solid which was used without further purification.

Provenance & Evidence