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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1286490Generated: October 31, 2026

3-Bromopyridine → Biphenyl

https://huagongshe.com/reaction/1286490

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromopyridineHCID 12286—
ReactantBenzenepropanolHCID 31234—
Reagent2-tert-Butyl-1,1,3,3-tetramethylguanidineHCID 3571581—
ReagentHCID 178489984HCID 178489984—
SolventDimethyl SulfoxideHCID 679—
ProductBiphenylHCID 7095—
Product3-BromopyridineHCID 12286—
ProductBenzenepropanolHCID 31234—
ProductHCID 97356607HCID 97356607—

Reaction Steps

The Mosquito was used to combine the source plate solutions by multi-aspiration of 250 nL of each of the four reaction components and then to dose the resulting reaction mixture (1 uL) into a 1536-well plate

Provenance & Evidence

DOI10.1126/science.1259203
Source datasetHTE Pd-catalyzed cross-coupling screen
ORD IDord-d7bc74a19d9b498c855dc93cc94938cc
Source noteHTE Pd-catalyzed cross-coupling screen