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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1286701Generated: October 30, 2026

3-Bromopyridine → Biphenyl

https://huagongshe.com/reaction/1286701

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromopyridineHCID 12286—
ReactantDiphenylphosphineHCID 70017—
Reagent2-((1,1-Dimethylethyl)imino)-N,N-diethylhexahydro-1,3-dimethyl-2lambda5-1,3,2-diazaphosphorin-2-amineHCID 3513851—
ReagentHCID 178505365HCID 178505365—
SolventDimethyl SulfoxideHCID 679—
ProductBiphenylHCID 7095—
Product3-BromopyridineHCID 12286—
ProductDiphenylphosphineHCID 70017—
ProductHCID 11334531HCID 11334531—

Reaction Steps

The Mosquito was used to combine the source plate solutions by multi-aspiration of 250 nL of each of the four reaction components and then to dose the resulting reaction mixture (1 uL) into a 1536-well plate

Provenance & Evidence

DOI10.1126/science.1259203
Source datasetHTE Pd-catalyzed cross-coupling screen
ORD IDord-2a7ab61bf90247cc8b9083d8e34a066c
Source noteHTE Pd-catalyzed cross-coupling screen