HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Malonate → Biphenyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Malonate | HCID 7761 | — |
| Reactant | 3-Bromopyridine | HCID 12286 | — |
| Reagent | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reagent | HCID 178420943 | HCID 178420943 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | Biphenyl | HCID 7095 | — |
| Product | Diethyl Malonate | HCID 7761 | — |
| Product | 3-Bromopyridine | HCID 12286 | — |
| Product | HCID 11310925 | HCID 11310925 | — |
Reaction Steps
The Mosquito was used to combine the source plate solutions by multi-aspiration of 250 nL of each of the four reaction components and then to dose the resulting reaction mixture (1 uL) into a 1536-well plate
Provenance & Evidence
| DOI | 10.1126/science.1259203 |
|---|---|
| Source dataset | HTE Pd-catalyzed cross-coupling screen |
| ORD ID | ord-75cf10be0b7149f6887ad56ab129a78d |
| Source note | HTE Pd-catalyzed cross-coupling screen |