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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1287170Generated: October 31, 2026

3-Bromopyridine → Biphenyl

https://huagongshe.com/reaction/1287170

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromopyridineHCID 12286—
Reactant1-Butyl-4-ethynylbenzeneHCID 2775132—
Reagenttert-Butylimino-tri(pyrrolidino)phosphoraneHCID 3856267—
ReagentHCID 178492611HCID 178492611—
SolventDimethyl SulfoxideHCID 679—
ProductBiphenylHCID 7095—
Product3-BromopyridineHCID 12286—
Product1-Butyl-4-ethynylbenzeneHCID 2775132—
ProductHCID 178440834HCID 178440834—

Reaction Steps

The Mosquito was used to combine the source plate solutions by multi-aspiration of 250 nL of each of the four reaction components and then to dose the resulting reaction mixture (1 uL) into a 1536-well plate

Provenance & Evidence

DOI10.1126/science.1259203
Source datasetHTE Pd-catalyzed cross-coupling screen
ORD IDord-819dbbd6d2dd4b43ba94775faf98542d
Source noteHTE Pd-catalyzed cross-coupling screen