HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 178484998, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 1-Cyano-2-methyl-3-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)isothiourea | HCID 103630 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178484998 | HCID 178484998 | — |
Reaction Steps
A solution of methylamine in ethanol (33%, 75 ml) was added to a solution of N-cyano-N'-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]-S-methylisothiourea (10.1 g) in ethanol (30 ml). The reaction mixture was set aside at room temperature for 2.5 hours. Following concentration under reduced pressure, the residue was recrystallised twice from isopropyl alcohol/petroleum ether, affording N-cyano-N'-methyl-N"-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]guanidine, m.p. 141°-143°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03984293 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-f1cf6cea3b9842788caac0f3048cd3f6 |
| Source note | uspto-grants-1976_10 |