L-Lysine monohydrochloride → Lysine, DL-
Reaction equation
Cl.[NH2:2][C@H:3]([C:9]([OH:11])=[O:10])[CH2:4][CH2:5][CH2:6][CH2:7][NH2:8]>O>[CH2:5]([CH2:4][CH:3]([NH2:2])[C:9]([OH:11])=[O:10])[CH2:6][CH2:7][NH2:8]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
In 10 ml of water is suspended 1.00 g. of CET. In the meantime, l-lysine hydrochloride is dissolved in water and the solution is passed over a basic ion exchange resin (Amberlite IRA-411 of Rohm and Haas Co., U.S.A.). The aqueous solution of free l-lysine base thus obtained (containing 0.37 g. of l-lysine) is added to the above suspension. The resultant pale-yellowish solution is lyophilized, whereupon a porous solid product is obtained. This product is recrystallized from a solvent mixture of water and ethanol to harvest crystalline CET-l-lysine salt. Yield: 70%.
Sources & evidence
- ORD record
- ord-5409adfaf63546a9bdd01083961994ab
- Source dataset
- uspto-grants-1976_10
- Patent number
- US03984403
Reaction notes
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