HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl Chloride → 1-Methyl-5-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl Chloride | HCID 6327 | — |
| Reactant | Sodium ethoxide | HCID 2723922 | — |
| Reactant | N-Desmethyl Dechloro Clobazam | HCID 10824683 | — |
| Product | 1-Methyl-5-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione | HCID 14697657 | — |
Reaction Steps
Starting from 1-phenyl 1,2,4,5tetrahydro 2,4-dioxo 3H-1,5-benzodiazepine, obtained in the Example VII, by acting methyl chloride in the presence of sodium ethanolate, there is obtained 1-phenyl 5-methyl 1,2,4,5-tetrahydro 2,4-dioxo 3H-1,5-benzodiazepine, melting at 144°-146° C. after recrystallisation in isopropanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03984398 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-cae1b3bcf6bf459494b38641d8f52a76 |
| Source note | uspto-grants-1976_10 |