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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1287292Generated: October 25, 2026

Methyl isothiocyanate → 5-(4-tert-Butyloxycarbonylaminobutyl)-3-methyl-2-thiohydantoin

https://huagongshe.com/reaction/1287292

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl isothiocyanateHCID 11167—
Reactant(S)-Methyl 2-amino-6-((tert-butoxycarbonyl)amino)hexanoateHCID 7018776—
Product5-(4-tert-Butyloxycarbonylaminobutyl)-3-methyl-2-thiohydantoinHCID 21507680—

Reaction Steps

Using an analogous procedure to Example 1 Nε-t-butyloxycarbonyl-L-lysine methyl ester may be reacted with methyl isothiocyanate to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03984430
Source datasetuspto-grants-1976_10
ORD IDord-d2413c6eb72640149f98efbe1fa3b0a4
Source noteuspto-grants-1976_10