Methyl isothiocyanate → HCID 21507683, compound

HRID 1287293Notes

Reaction equation

HRID 1287293 reaction equation
CO[C:3](=[O:22])[C@H:4]([CH2:6][CH2:7][CH2:8][CH2:9][NH:10][C:11]([O:13][CH2:14][C:15]1[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=1)=[O:12])[NH2:5].[CH3:23][N:24]=[C:25]=[S:26]>>[Cl:21][C:18]1[CH:17]=[CH:16][C:15]([CH2:14][O:13][C:11]([NH:10][CH2:9][CH2:8][CH2:7][CH2:6][CH:4]2[NH:5][C:25](=[S:26])[N:24]([CH3:23])[C:3]2=[O:22])=[O:12])=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 11167Methyl isothiocyanateHCID 131710473HCID 131710473, compound

Product 1

HCID 21507683HCID 21507683, compound

Procedure

Using an analogous procedure to Example 1 Nε-p-chlorobenzyloxycarbonyl-L-lysine methyl ester may be reacted with methyl isothiocyanate to give the title compound.

Sources & evidence

ORD record
ord-4656fd2016d842719dc3d18e2575545f
Source dataset
uspto-grants-1976_10
Patent number
US03984430

Reaction notes

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