Methyl isothiocyanate → HCID 21507684, compound

HRID 1287299Notes

Reaction equation

CO[C:3](=[O:22])[C@H:4]([CH2:7][CH2:8][CH2:9][CH2:10][NH:11][C:12]([O:14][CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)=[O:13])[NH:5][CH3:6].[CH3:23][N:24]=[C:25]=[S:26]>>[CH2:15]([O:14][C:12]([NH:11][CH2:10][CH2:9][CH2:8][CH2:7][CH:4]1[N:5]([CH3:6])[C:25](=[S:26])[N:24]([CH3:23])[C:3]1=[O:22])=[O:13])[C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1

Participants

Reactant 2

HCID 11167Methyl isothiocyanate

HCID 13945166HCID 13945166, compound

Product 1

HCID 21507684HCID 21507684, compound

Procedure

Using an analogous procedure to Example 1 Nε-benzyloxycarbonyl-Nα-methyl-L-lysine methyl ester may be reacted with methyl isothiocyanate to give the title compound.

Sources & evidence

ORD record: ord-f24d8984a0f342ba8fdc30677d8ced88
Source dataset: uspto-grants-1976_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03984430

Reaction notes

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