HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → HCID 21444968, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | 1-{2-[(Oxiran-2-yl)methoxy]phenyl}-1H-pyrrole | HCID 13755510 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 21444968 | HCID 21444968 | — |
Reaction Steps
A solution of 15 g of 1-[o-(pyrrol-1-yl)-phenoxy]-2,3-epoxy-propane and 7 g of morpholine in 150 ml of isopropanol is heated for 2 hours to the boil under reflux. After evaporation in vacuo, an oil remains, which crystallises and after recrystallisation from butanone gives 1-morpholino-3-[o-(pyrrol-1-yl)-phenoxy]-2-propanol of melting point 81°-82° C. It forms a neutral fumarate of melting point 136°-137° C (from butanone).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03984436 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-091dd09e3ea0402fa0f38edb54665988 |
| Source note | uspto-grants-1976_10 |