Sodium Hydroxide → 2-Methyl-6-phenoxy-hexanoic acid

HRID 1287352Notes

Reaction equation

HRID 1287352 reaction equation
C([O:3][C:4](=[O:23])[C:5](C)([CH2:11][CH2:12][CH2:13][CH2:14][O:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:6](OCC)=O)C.[OH-].[Na+]>C(O)C>[CH3:6][CH:5]([CH2:11][CH2:12][CH2:13][CH2:14][O:15][C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1)[C:4]([OH:23])=[O:3]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 53773953Methyl-(4-phenoxybutyl)-malonic acid diethyl ester

Product 1

HCID 203221352-Methyl-6-phenoxy-hexanoic acid

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

242 g of methyl-(4-phenoxybutyl)-malonic acid diethyl ester, 1000 ml of a 20% sodium hydroxide solution and 100 ml of ethanol were refluxed for 12 hours.

Sources & evidence

ORD record
ord-ccaf67c542334502b14d842f0ac3f453
Source dataset
uspto-grants-1976_10
Patent number
US03984459

Reaction notes

Loading…