HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → 1-(4-Chlorophenyl)-3-octanimidoylurea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | 4-Chlorophenyl Isocyanate | HCID 7693 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | Octanamidine hydrochloride | HCID 86734052 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 1-(4-Chlorophenyl)-3-octanimidoylurea | HCID 152746825 | — |
Reaction Steps
Following a procedure similar to that described in Example 1 but using 2.2 g. sodium in 200 ml. dry acetone, 17.8 g. octanamidine hydrochloride, and 15.3 g. 4-chlorophenyl isocyanate in 100 ml. benzene, there was obtained after recrystallization from acetonitrile 19.7 g. of the hydrochloride of 1-(4-chlorophenyl)-3-(octanimidoyl)urea; m.p. 156°-165°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03984467 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-738c120d47aa40bfad1356532b655e4c |
| Source note | uspto-grants-1976_10 |