3-Methoxybenzaldehyde → 5-[(3-Methoxyphenyl)methylene]-3-methyl-2,4-imidazolidinedione

HRID 128739Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][CH:10]=1)[CH:6]=O.[CH3:11][N:12]1[C:16](=[O:17])[CH2:15][NH:14][C:13]1=[O:18]>>[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:6]=[C:15]2[NH:14][C:13](=[O:18])[N:12]([CH3:11])[C:16]2=[O:17])[CH:8]=[CH:9][CH:10]=1

Participants

Reactant 2

HCID 115693-Methoxybenzaldehyde

HCID 1388512,4-Imidazolidinedione, 3-methyl-

Product 1

HCID 542255625-[(3-Methoxyphenyl)methylene]-3-methyl-2,4-imidazolidinedioneYield 73.8%

Procedure

Prepared according to the procedure described in Example 93 using 3-methoxybenzaldehyde (3.5 ml, 28 mmoles) and 3-methyl hydantoin (3.0 g, 21 mmoles), to afford the product (3.6 g), mp 203°-205° C.

Workup

customPrepared

Sources & evidence

ORD record: ord-0c93bb905e144a9b8e046d2e36fecf85
Source dataset: uspto-grants-1995_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05464856

Reaction notes

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