Acetone → HCID 178444020, compound

Participants

Reaction Steps

Following a procedure similar to that described in Example 42 but using 2.3 g. sodium in 300 ml. dry acetone, 16.4 g. heptanamidine hydrochloride, and 21.4 g. 4-chloro-3-nitrophenyl isothiocyanate (m.p. 54°-56°C., prepared from 4-chloro-3-nitroaniline) in 100 ml. dry acetone there was obtained 1-(4-chloro-3-nitrophenyl)-3-(heptanimidoyl)-2-thiourea, m.p. 92°-94°C. (from benzene-n-pentane); hydrochloride (22.5 g.), m.p. 138°-140°C. (from acetonitrile).

Provenance & Evidence