4-Chlorophenyl Isocyanate → HCID 56628965, compound

HRID 1287488Notes

Reaction equation

HRID 1287488 reaction equation
N1C=CC=CC=1N1[C:12](=[S:13])[N:11]2[CH:14]=[CH:15][CH:16]=[CH:17][C:10]2=[N:9]C1=S.[Cl:19][C:20]1[CH:25]=[CH:24][C:23]([N:26]=[C:27]=[O:28])=[CH:22][CH:21]=1>C(#N)C>[Cl:19][C:20]1[CH:25]=[CH:24][C:23]([N:26]2[C:12](=[S:13])[N:11]3[CH:14]=[CH:15][CH:16]=[CH:17][C:10]3=[N:9][C:27]2=[O:28])=[CH:22][CH:21]=1

Participants

4

Reactant 2

HCID 76934-Chlorophenyl IsocyanateHCID 2907853-(Pyridin-2-yl)-2H-pyrido[1,2-a][1,3,5]triazine-2,4(3H)-dithione

Product 1

HCID 56628965HCID 56628965, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Conditions

Temperature
70 °C

Procedure

544 Mg. of 3-(2-pyridyl) pyrido (1,2-a) 1,3,5-triazine-2,4-dithione is combined with p-chloro phenylisocyanate and 10 ml. of acetonitrile. The reaction mixture is heated at 70° C. for 1 hour with a precipitate appearing after 1/2 hour. The reaction mixture is allowed to cool to room temperature with stirring. The solid material is filtered, washed twice with acetone, once with ether and dried in vacuo affording 3-(4-chlorophenyl) pyrido (1,2-a) 1,3,5-triazine-2-one-4-thione m.p. 209°-212° C.

Workup

  1. temperatureto cool to room temperature
  2. filtrationThe solid material is filtered
  3. washwashed twice with acetone, once with ether
  4. customdried in vacuo

Sources & evidence

ORD record
ord-821179e0aae84094aa57c0e3eff02dbf
Source dataset
uspto-grants-1976_10
Patent number
US03984549

Reaction notes

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