化工社化工社 化学情報印刷レポート · 研究参考用
DL-Glutamic acid → N-Lauroyl-DL-glutamic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | DL-Glutamic acid | HCID 611 | — |
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Disodium glutamate | HCID 167560 | — |
| 反応物 | Lauric acid sulfuric acid | HCID 19758976 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 溶媒 | Water | HCID 962 | — |
| 生成物 | N-Lauroyl-DL-glutamic acid | HCID 351563 | — |
反応手順
DL-Glutamic acid 14.7 g was suspended in 75 ml water and 45 ml acetone and then added 8 g of sodium hydroxide. To the solution of the sodium glutamate was added lauric acid-sulfuric acid mixed anhydride with 10 N sodium hydroxide at pH 12 - 13 on the ice bath with stirring. The reaction mixture was stirred for an additional 1 hour, then treated by the same manner as in Example 1. N-Lauroyl-DL-glutamic acid was obtained 19.7 g (59.7 %) M.P. 116° - 119°C.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US03985722 |
| 出典データセット | uspto-grants-1976_10 |
| ORD ID | ord-facafe52fdfa4251be80681e2badce34 |
| 出典メモ | uspto-grants-1976_10 |