HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 2-Bromo-7-chloro-3,4-dihydronaphthalen-1(2H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 7-Chloro-1,2,3,4-tetrahydronaphthalen-1-one | HCID 256677 | — |
| Solvent | Carbon Disulfide | HCID 6348 | — |
| Product | 2-Bromo-7-chloro-3,4-dihydronaphthalen-1(2H)-one | HCID 12206526 | — |
Reaction Steps
To a solution of 7-chloro-1-tetralone, 204.3 g, (1.1 moles), in carbon disulfide (1.08 liters) there is dropwise, with stirring, 176 g (1.1 moles) of bromine in 540 ml carbon disulfide at 0°-5° C. After stirring for an additional 30 minutes, the solvent is removed, giving a dark brown syrup, weighing 315 g. The crude product is used as is in the following step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03985731 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-d1851919117d47388cc46d028467cc9e |
| Source note | uspto-grants-1976_10 |