Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1287606Generated: November 1, 2026

Phosphorus tribromide → 3-Bromo-7-cyanomethylthioacetamido-3-cephem-4-Carboxylic Acid Benzhydryl Ester

https://huagongshe.com/reaction/1287606

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhosphorus tribromideHCID 24614—
Reactant7-Cyanomethylthioacetamido-3-cephem-3-ol-4-carboxylic acid Benzhydryl EsterHCID 131710480—
Product3-Bromo-7-cyanomethylthioacetamido-3-cephem-4-Carboxylic Acid Benzhydryl EsterHCID 131710484—

Reaction Steps

The desired product is prepared from 7-cyanomethylthioacetamido-3-cephem-3-ol-4-carboxylic acid benzhydryl ester using the procedure described in Example 5, but replacing phosphorus trichloride with phosphorus tribromide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03985746
Source datasetuspto-grants-1976_10
ORD IDord-00373c9006e94f5584bd87cd98e6f6ce
Source noteuspto-grants-1976_10