HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dodecanoyl chloride → HCID 21505569, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dodecanoyl chloride | HCID 8166 | — |
| Reactant | 3-{4-[8-(Methylsulfanyl)-10,11-dihydrodibenzo[b,f]thiepin-10-yl]piperazin-1-yl}propan-1-ol | HCID 147577 | — |
| Solvent | Benzene | HCID 241 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 21505569 | HCID 21505569 | — |
Reaction Steps
In accordance with the general procedure described in the foregoing Examples, 14.0 grams of 8-methylthio-10-[4-(3-hydroxypropyl)piperazino]-10,11-dihydrodibenzo[b,f]thiepin was reacted with 15.3 grams of lauroyl chloride (dodecanoyl chloride) in a mixture of benzene and chloroform. In this manner, 8-methylthio-10-[4-(3-dodecanoyloxypropyl)piperazino]-10,11-dihydrodibenzo[b,f]thiepin was obtained. The pure base was a viscous oil which formed a crystalline di(hydrogen maleate) that had a melting point of 121°-122°C, after recrystallization from acetone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03985750 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-aaec42fcf47c4cb89cad8b21541faaf7 |
| Source note | uspto-grants-1976_10 |