Diphenyl Ether → HCID 178519681, compound

Participants

Reaction Steps

7.3 g. of α-[[[1-(2-furanylmethyl)- 1H-pyrazol-5-yl]-amino]methylene]-β-oxo-3-pyridinepropanoic acid, ethyl ester (0.02 mol.) are heated in 20 ml. of diphenylether at 250° for 10 minutes. The mixture is cooled to room temperature and 20 ml. of ether are added. The product, [1-(2-furanylmethyl)-4-hydroxy-1H-pyrazolo]3,4 -b]pyridin-5-yl]-3-pyridylmethanone precipitates and is recrystallized from butyl alcohol, yield 3.8 g. (60%); m.p. 152°-153°.

Provenance & Evidence