Iodoethane → HCID 21505667, compound

Participants

Reaction Steps

3.3 g. of [1-(2-furanylmethyl)-4-hydroxy-1H-pyrazolo[ 3,4-b]pyridine-5-yl]-2-thienylmethanone (0.01 mol.), 1.5 g. of potassium carbonate (0.011 mol.) and 3.1 g. of ethyl iodide (0.02 mol.) are stirred together in 20 ml. of dimethylformamide at 70° for 12 hours. After this time, the inorganic precipitate is filtered off and the filtrate treated with about 10 ml. of water. The product, [4-Ethoxy-1-(2-furanylmethyl)-1H-pyrazolo[ 3,4-b]pyridin-5-yl]-2-thienylmethanone, crystallizes on standing, yield 3 g. (86%); m.p. 85°-87° (methanol).

Provenance & Evidence