Selenium Dioxide → HCID 21505670, compound

Participants

Reaction Steps

3.5 g. of [4-ethoxy-1-(2-furanylmethyl)-1H-pyrazolo[3,4-b]pyridin-5-yl]-2-thienylmethanone (0.01 mol.) are treated with 1.22 g. of selenium dioxide (0.011 mol.) in 20 ml. of diethyleneglycol dimethylether at reflux temperature for 1.5 hours with stirring. The precipitated selenium is filtered off and the solution is evaporated to dryness in vacuo. The remaining product, (4-ethoxy-1H-pyrazolo[3,4-b]pyridin-5-yl]-2-thienylmethanone, is recrystallized from butanol, yield 2 g. (75%); m.p. 202°-205°.

Provenance & Evidence