Methanol → HCID 21505637, compound

Participants

Reaction Steps

To a 1.8 g. portion of 4-(5-cyclopropyl-1,2,4-oxadiazol- 3-yl)-1-[3-(p-fluorobenzoyl)-propyl]pyridinium perchlorate, prepared as described in Example 3, in 80 ml. of methanol is added, portionwise with stirring, 1.8 g. of sodium borohydride. The mixture is stirred for 2 hours and then poured into 300 ml. of cold water, causing a white solid to separate. This solid is collected and recrystallized from acetonitrile, m.p. 89°-92° C.

Provenance & Evidence