HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Methyl-5-nitro-2-(pyridin-2-yl)-1,3-benzoxazole → 6-Methyl-2-(pyridin-2-yl)-1,3-benzoxazol-5-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Methyl-5-nitro-2-(pyridin-2-yl)-1,3-benzoxazole | HCID 12781872 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 6-Methyl-2-(pyridin-2-yl)-1,3-benzoxazol-5-amine | HCID 21505653 | 87.8% |
Reaction Steps
A suspension of 6-methyl-5-nitro-2-(2-pyridinyl)benzoxazole (10.0 g, 0.044 mole) and platinum oxide (1.0 g) in 150 ml of ethanol is hydrogenated over a period of 2 hours. The catalyst is separated by filtration and the ethanol removed under vacuum yielding 8.7 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03985755 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-40965b7c61254712aa62f8b5df0e32d0 |
| Source note | uspto-grants-1976_10 |