3-Nitro-5-sulphamyl-4-(m-toluidino)-benzoic acid → Benzoic acid,3-amino-5-(aminosulfonyl)-4-[(3-methylphenyl)amino]-

HRID 1287725Notes

Reaction equation

HRID 1287725 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([S:21](=[O:24])(=[O:23])[NH2:22])[C:12]=1[NH:13][C:14]1[CH:15]=[C:16]([CH3:20])[CH:17]=[CH:18][CH:19]=1)[C:7]([OH:9])=[O:8])([O-])=O.N(C1C(S(=O)(=O)N)=CC(C(O)=O)=CC=1[N+]([O-])=O)C1C=CC=CC=1>>[NH2:1][C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([S:21](=[O:24])(=[O:23])[NH2:22])[C:12]=1[NH:13][C:14]1[CH:15]=[C:16]([CH3:20])[CH:17]=[CH:18][CH:19]=1)[C:7]([OH:9])=[O:8]

Participants

3

Reactant 2

HCID 215059883-Nitro-5-sulphamyl-4-(m-toluidino)-benzoic acidHCID 215060714-Anilino-3-nitro-5-sulphamyl-benzoic acid

Product 1

HCID 21506124Benzoic acid,3-amino-5-(aminosulfonyl)-4-[(3-methylphenyl)amino]-

Procedure

By substituting 3-nitro-5-sulphamyl-4-(m-toluidino)-benzoic acid for the 4-anilino-3-nitro-5-sulphamyl-benzoic acid of Example 9 B, the above compound was obtained with a melting point of 280°-282° C after recrystallization from ethanol.

Workup

  1. customthe above compound was obtained with a melting point of 280°-282° C
  2. customafter recrystallization from ethanol

Sources & evidence

ORD record
ord-43a2037731c7411d941c5da6744941ba
Source dataset
uspto-grants-1976_10
Patent number
US03985777

Reaction notes

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