4-Anilino-3-nitro-5-sulphamyl-benzoic acid → Benzoic acid,3-amino-5-(aminosulfonyl)-4-[(3-methoxyphenyl)amino]-

HRID 1287729Notes

Reaction equation

HRID 1287729 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:23]=[CH:24][CH:25]=1)[NH:6][C:7]1[C:15]([S:16](=[O:19])(=[O:18])[NH2:17])=[CH:14][C:10]([C:11]([OH:13])=[O:12])=[CH:9][C:8]=1[N+:20]([O-])=O.N(C1C(S(=O)(=O)N)=CC(C(O)=O)=CC=1[N+]([O-])=O)C1C=CC=CC=1>>[NH2:20][C:8]1[CH:9]=[C:10]([CH:14]=[C:15]([S:16](=[O:19])(=[O:18])[NH2:17])[C:7]=1[NH:6][C:5]1[CH:23]=[CH:24][CH:25]=[C:3]([O:2][CH3:1])[CH:4]=1)[C:11]([OH:13])=[O:12]

Participants

3

Reactant 2

HCID 215060714-Anilino-3-nitro-5-sulphamyl-benzoic acidHCID 215061094-(m-Methoxyanilino)-3-nitro-5-sulphamyl-benzoic acid

Product 1

HCID 21505994Benzoic acid,3-amino-5-(aminosulfonyl)-4-[(3-methoxyphenyl)amino]-

Procedure

By substituting 4-(m-methoxyanilino)-3-nitro-5-sulphamyl-benzoic acid for the 4-anilino-3-nitro-5-sulphamyl-benzoic acid of Example 9 B, the above compound was obtained with a melting point of 232°-234° C after recrystallization from aqueous methanol.

Workup

  1. customthe above compound was obtained with a melting point of 232°-234° C
  2. customafter recrystallization from aqueous methanol

Sources & evidence

ORD record
ord-8b58a80ce5a74564ae6cad33734207d6
Source dataset
uspto-grants-1976_10
Patent number
US03985777

Reaction notes

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