4-Anilino-3-nitro-5-sulphamyl-benzoic acid → 3-Amino-4-(p-methoxyanilino)-5-sulphamyl-benzoic acid

HRID 1287730Notes

Reaction equation

HRID 1287730 reaction equation
[CH3:1][O:2][C:3]1[CH:25]=[CH:24][C:6]([NH:7][C:8]2[C:16]([S:17](=[O:20])(=[O:19])[NH2:18])=[CH:15][C:11]([C:12]([OH:14])=[O:13])=[CH:10][C:9]=2[N+:21]([O-])=O)=[CH:5][CH:4]=1.N(C1C(S(=O)(=O)N)=CC(C(O)=O)=CC=1[N+]([O-])=O)C1C=CC=CC=1>>[NH2:21][C:9]1[CH:10]=[C:11]([CH:15]=[C:16]([S:17](=[O:20])(=[O:19])[NH2:18])[C:8]=1[NH:7][C:6]1[CH:24]=[CH:25][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1)[C:12]([OH:14])=[O:13]

Participants

3

Reactant 2

HCID 215060714-Anilino-3-nitro-5-sulphamyl-benzoic acidHCID 215060864-(p-Methoxyanilino)-3-nitro-5-sulphamyl-benzoic acid

Product 1

HCID 215059853-Amino-4-(p-methoxyanilino)-5-sulphamyl-benzoic acid

Procedure

By substituting 4-(p-methoxyanilino)-3-nitro-5-sulphamyl-benzoic acid for the 4-anilino-3-nitro-5-sulphamyl-benzoic acid of Example 9 B, the above compound was obtained with a melting point of 214°C.

Workup

  1. customthe above compound was obtained with a melting point of 214°C.

Sources & evidence

ORD record
ord-05613ec5bc784c49b0bcb8927fc9dc38
Source dataset
uspto-grants-1976_10
Patent number
US03985777

Reaction notes

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