3-(Aminosulfonyl)-5-nitro-4-phenoxybenzoic acid → 3-Amino-4-(p-hydroxyanilino)-5-sulphamyl-benzoic acid

HRID 1287734Notes

Reaction equation

HRID 1287734 reaction equation
[OH:1][C:2]1[CH:24]=[CH:23][C:5]([NH:6][C:7]2[C:15]([S:16](=[O:19])(=[O:18])[NH2:17])=[CH:14][C:10]([C:11]([OH:13])=[O:12])=[CH:9][C:8]=2[N+:20]([O-])=O)=[CH:4][CH:3]=1.[N+](C1C=C(C=C(S(=O)(=O)N)C=1OC1C=CC=CC=1)C(O)=O)([O-])=O>>[NH2:20][C:8]1[CH:9]=[C:10]([CH:14]=[C:15]([S:16](=[O:19])(=[O:18])[NH2:17])[C:7]=1[NH:6][C:5]1[CH:23]=[CH:24][C:2]([OH:1])=[CH:3][CH:4]=1)[C:11]([OH:13])=[O:12]

Participants

3

Reactant 2

HCID 1199263-(Aminosulfonyl)-5-nitro-4-phenoxybenzoic acidHCID 215060794-(p-Hydroxyanilino)-3-nitro-5-sulphamyl-benzoic acid

Product 1

HCID 215061523-Amino-4-(p-hydroxyanilino)-5-sulphamyl-benzoic acid

Procedure

By substituting 4-(p-hydroxyanilino)-3-nitro-5-sulphamyl-benzoic acid (10 g) for the 3-nitro-4-phenoxy-5-sulphamyl-benzoic acid of Example 1 B, the above compound was obtained with a melting point of 296° C (decomp.).

Workup

  1. customthe above compound was obtained with a melting point of 296° C (decomp.)

Sources & evidence

ORD record
ord-591c38f6843b4bb79284ee90141eeed6
Source dataset
uspto-grants-1976_10
Patent number
US03985777

Reaction notes

Loading…