2-Methoxyethylamine → HCID 21506036, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 4-chloro-3-nitro-5-sulphamyl-benzoic acid (4.2 g), 2-methoxyethylamine (5.6 g), and 50% ethanol (10 ml) was heated to 60° C for 1 hour. The ethanol was distilled off under reduced pressure, and the resulting 4-(2-methoxyethylamino)-3-nitro-5-sulphamyl-benzoic acid was precipitated by addition of 4N hydrochloric acid until pH 2. After recrystallization from water, the melting point was 192°-194° C. The compound crystallized with 1 molecule of water of crystallization.

Provenance & Evidence