4-Anilino-3-nitro-5-sulphamyl-benzoic acid → 3-Amino-4-piperidino-5-sulphamyl-benzoic acid

HRID 1287745Notes

Reaction equation

HRID 1287745 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([S:19](=[O:22])(=[O:21])[NH2:20])[C:12]=1[N:13]1[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1)[C:7]([OH:9])=[O:8])([O-])=O.N(C1C(S(=O)(=O)N)=CC(C(O)=O)=CC=1[N+]([O-])=O)C1C=CC=CC=1>>[NH2:1][C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([S:19](=[O:21])(=[O:22])[NH2:20])[C:12]=1[N:13]1[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1)[C:7]([OH:9])=[O:8]

Participants

3

Reactant 2

HCID 215060714-Anilino-3-nitro-5-sulphamyl-benzoic acidHCID 215061073-Nitro-4-piperidino-5-sulphamyl-benzoic acid

Product 1

HCID 215061343-Amino-4-piperidino-5-sulphamyl-benzoic acid

Procedure

By substituting 3-nitro-4-piperidino-5-sulphamyl-benzoic acid for the 4-anilino-3-nitro-5-sulphamyl-benzoic acid of Example 9 B, the above compound was obtained with a melting point of 279° C (decomp.) after recrystallization from aqueous methanol.

Workup

  1. customthe above compound was obtained with a melting point of 279° C (decomp.)
  2. customafter recrystallization from aqueous methanol

Sources & evidence

ORD record
ord-0575dff72e2b47b48399debe67cea41d
Source dataset
uspto-grants-1976_10
Patent number
US03985777

Reaction notes

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