Thionyl Chloride → 3-Nitro-4-phenoxy-5-sulfamoylbenzoyl chloride

HRID 1287763Notes

Reaction equation

HRID 1287763 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([S:20](=[O:23])(=[O:22])[NH2:21])[C:12]=1[O:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:7](O)=[O:8])([O-:3])=[O:2].S(Cl)([Cl:26])=O>>[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[C:11]([S:20](=[O:23])(=[O:22])[NH2:21])[C:12]=1[O:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:7]([Cl:26])=[O:8])([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 1199263-(Aminosulfonyl)-5-nitro-4-phenoxybenzoic acid

Product 1

HCID 215060353-Nitro-4-phenoxy-5-sulfamoylbenzoyl chloride

Procedure

A mixture of 3-nitro-4-phenoxy-5-sulphamyl-benzoic acid (5 g) and thionyl chloride (50 ml) was heated on a steam bath for 5 hours. After evaporation in vacuo to dryness, the compound was obtained as a crude product, which was used in the next step without further purification.

Workup

  1. temperaturewas heated on a steam bath for 5 hours
  2. customAfter evaporation in vacuo to dryness

Sources & evidence

ORD record
ord-aaba54c2c25f45eabe39853ccc1fe8e0
Source dataset
uspto-grants-1976_10
Patent number
US03985777

Reaction notes

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