HCID 21506015, compound → HCID 21505997, compound

HRID 1287777Notes

Reaction equation

HRID 1287777 reaction equation
C([O:3][C:4](=[O:36])[C:5]1[CH:10]=[C:9]([S:11](=[O:20])(=[O:19])[NH:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[C:8]([NH:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[C:7]([NH:28][CH2:29][C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[CH:6]=1)C>[OH-].[Na+]>[NH:21]([C:8]1[C:9]([S:11](=[O:20])(=[O:19])[NH:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[CH:10][C:5]([C:4]([OH:36])=[O:3])=[CH:6][C:7]=1[NH:28][CH2:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1)[C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1

Participants

3

Reactant 1

HCID 21506015HCID 21506015, compound

Product 1

HCID 21505997HCID 21505997, compound

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

A solution of ethyl-4-anilino-3-benzylamino-5-phenylsulphamyl-benzoate (3 g) in 1N sodium hydroxide (30 ml) was heated on a steam bath for 1 hour. The 4-anilino-3-benzylamino-5-phenylsulphamyl-benzoic acid was precipitated by addition of 4N hydrochloric acid until pH 2, and recrystallized from acetone-water and 80% ethanol in water; the melting point was 243° C.

Workup

  1. customThe 4-anilino-3-benzylamino-5-phenylsulphamyl-benzoic acid was precipitated by addition of 4N hydrochloric acid until pH 2
  2. customrecrystallized from acetone-water and 80% ethanol in water

Sources & evidence

ORD record
ord-87d9578b66864e86b4f9d56ed4f96be2
Source dataset
uspto-grants-1976_10
Patent number
US03985777

Reaction notes

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