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HRID1287808

反应详情

EQUATION

反应方程式

HRID 1287808 的结构方程式

REACTANTS

反应物

2
结构：[Na+].[OH-]
HCID14798

Sodium Hydroxide

HNaO

结构：CCOC(=O)c1cc(NCc2ccccc2)c(Oc2ccccc2)c(S(=O)(=O)N(C)C)c1
HCID21506051

未命名化合物

PRODUCTS

生成物

1
结构：CN(C)S(=O)(=O)c1cc(C(=O)O)cc(NCc2ccccc2)c1Oc1ccccc1
HCID21505993

未命名化合物

PROCEDURE

实验过程

Ethyl 3-benzylamino-5 -dimethylsulphamyl-4-phenoxy-benzoate (1 g) was heated on a steam bath with 1N sodium hydroxide (15ml) for 6 hours. From the resulting solution, the 3-benzylamino-5-dimethylsulphamyl-4-phenoxy-benzoic acid was precipitated by addition of 4N hydrochloric acid until a pH of 2.5. After isolating and recrystallizing from aqueous ethanol, the compound was obtained with a melting point of 205°-206° C.

WORKUP

后处理

  1. customFrom the resulting solution, the 3-benzylamino-5-dimethylsulphamyl-4-phenoxy-benzoic acid was precipitated by addition of 4N hydrochloric acid until a pH of 2.5
  2. customAfter isolating
  3. customrecrystallizing from aqueous ethanol
  4. customthe compound was obtained with a melting point of 205°-206° C.