HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Naphthol → Ethyl 6-(2-naphthyloxy)hexanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Naphthol | HCID 8663 | — |
| Reactant | Ethyl 6-bromohexanoate | HCID 117544 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | Ethyl 6-(2-naphthyloxy)hexanoate | HCID 19375098 | — |
Reaction Steps
Ethyl 6-bromohexanoate and the sodium salt of 2-naphthol are reacted in DMF at 70° to provide ethyl 6-(2-naphthyloxy)hexanoate, which after the usual workup is reduced with lithium aluminum hydride in THF to provide 6-(2-naphthyloxy)hexanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05464865 |
| Source dataset | uspto-grants-1995_11 |
| ORD ID | ord-cbe01735c94b4625940887766daee71c |
| Source note | uspto-grants-1995_11 |