HuagongsheHuagongshe Chemistry Print Report · For research reference only
Nitric Acid → 6-Methoxy-5-nitro-2-(pyridin-2-yl)-1,3-benzothiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Nitric Acid | HCID 944 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 6-Methoxy-2-(pyridin-2-yl)-1,3-benzothiazole | HCID 21506688 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | 6-Methoxy-5-nitro-2-(pyridin-2-yl)-1,3-benzothiazole | HCID 21506686 | — |
Reaction Steps
6-Methoxy -2-(pyridinyl)benzothiazole, 30 g, (0.124 mole) is dissolved in 115 cc of concentrated H2SO4 and cooled to 0°. Nitric acid, 7.9 cc (0.124 mole) is added and the solution stirred for 2 hours at room temperature. The reaction mixture is poured on ice and the pH adjusted to 10 with 50% NaOH solution. The precipitate is filtered and dried to yield 11 g of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03985885 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-f39473ce744d4053b8de0f76a348e28c |
| Source note | uspto-grants-1976_10 |