HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chlorobenzaldehyde → HCID 12308272, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chlorobenzaldehyde | HCID 11477 | — |
| Reactant | Methyl 3-amino-3-ethoxyprop-2-enoate | HCID 71366473 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 12308272 | HCID 12308272 | 78% |
Reaction Steps
Upon heating a solution of 7.1 g of 3-chlorobenzaldehyde and 14.5 g of 3-amino-3-ethoxyacrylic acid methyl ester in 50 ml of isopropanol for 6 hours, 2-amino-4-(3-chlorophenyl)-6-ethoxy-4,5-dihydropyridine-3,5-dicarboxylic acid dimethyl ester of melting point 158° C (isopropanol) is obtained. Yield 78% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03985886 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-d6470c2bb8e3464a98027ce8a1fb5fe6 |
| Source note | uspto-grants-1976_10 |