HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-5-nitrobenzaldehyde → HCID 12308274, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-5-nitrobenzaldehyde | HCID 72933 | — |
| Reactant | beta-Aminobeta-ethoxyacrylic acid ethyl ester | HCID 278451 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 12308274 | HCID 12308274 | 65% |
Reaction Steps
Upon heating a solution of 9.3 g of 3-nitro-6-chlorobenzaldehyde and 15.9 g of 3-amino-3-ethoxyacrylic acid ethyl ester in 50 ml of isopropanol for 6 hours, 2-amino-4-(3-nitro-6-chlorophenyl)-6-ethoxy-4,5-dihydropyridine-3,5-dicarboxylic acid diethyl ester of melting point 136°-37° C (isopropanol) is obtained. Yield: 65% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03985886 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-d2b8a27eec8d453a819fb57d5d1673a0 |
| Source note | uspto-grants-1976_10 |